Peyronie’s Disease

Peyronie’s disease (also known as indurations plastica penis) is an acquired inflammatory condition of the penis. The principle manifestation of Peyronie’s disease is the formation of a plaque (a segment of flat scar tissue) within the tissues of the penis. This plaque can usually be felt through the penile skin. The plaque is not a tumor but it may lead to serious problems such as curved and/or painful erections.

Risk Factors

Unfortunately, there is no ability to control what increases your risk of getting Peyronie’s Disease.  There are multiple factors that can affect your chances of having this disease, including:

  • Family history
  • Connective tissue disorders
  • Age


There are multiple symptoms that may indicate you have Peyronie’s Disease including:

  • Scar tissue
  • A significant bend to the penis
  • Erection problems
  • Shortening of the penis


This disease can affect your quality of life so it is important to go see a doctor if you think you might have it.  There are a few ways that doctors could diagnose Peyronie’s Disease including:

  • physical exam
  • injection and examination of the penis
  • ultrasound


There are several different ways that Peyronie’s Disease can be treated including oral drugs, penile injections, and for very serious cases, surgery.  Your doctor will be able to provide you with more information about each form of treatment, and help you decide which one will be right for you.

How May We Help?

Call us: (864) 797-7450

Is Xiaflex Right For You?

Xiaflex is a prescription medicine used to treat adult men with Peyronie’s disease who have a “plaque” that can be felt and a curve in their penis greater than 30 degrees when treatment is started.

It is an injectable medicine that can result in significant straightening of the penis.  It is the only FDA-approved non-surgical treatment for the management of Peyronie’s disease, and is the only medication recommended by the American Urological Association.

Xiaflex works by breaking down collagen within the plaque, resulting in improvements in curvature.  It is administered quickly and easily in our offices here at Regional Urology, and is typically given as a series of treatments.